Discovery of a small molecule inhibitor targeting dengue virus NS5 RNA-dependent RNA polymerase

Dengue is a mosquito-borne viral infection that has spread globally in recent years. Around half of the world’s population, especially in the tropics and subtropics, is at risk of infection. Every year, 50–100 million clinical cases are reported, and more than 500,000 patients develop the symptoms o...

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Detalles Bibliográficos
Autores principales: Shimizu, Hideaki, Saito, Akatsuki, Mikuni, Junko, Nakayama, Emi E., Koyama, Hiroo, Honma, Teruki, Shirouzu, Mikako, Sekine, Shun-ichi, Shioda, Tatsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886872/
https://www.ncbi.nlm.nih.gov/pubmed/31738758
http://dx.doi.org/10.1371/journal.pntd.0007894

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886872/
https://www.ncbi.nlm.nih.gov/pubmed/31738758
http://dx.doi.org/10.1371/journal.pntd.0007894

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