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DNA variants affecting the expression of numerous genes in trans have diverse mechanisms of action and evolutionary histories

DNA variants that alter gene expression contribute to variation in many phenotypic traits. In particular, trans-acting variants, which are often located on different chromosomes from the genes they affect, are an important source of heritable gene expression variation. However, our knowledge about t...

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Detalles Bibliográficos
Autores principales: Lutz, Sheila, Brion, Christian, Kliebhan, Margaret, Albert, Frank W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886874/
https://www.ncbi.nlm.nih.gov/pubmed/31738765
http://dx.doi.org/10.1371/journal.pgen.1008375