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Single-Cell Chromatin Analysis of Mammary Gland Development Reveals Cell-State Transcriptional Regulators and Lineage Relationships

Technological improvements enable single-cell epigenetic analyses of organ development. We reasoned that high-resolution single-cell chromatin accessibility mapping would provide needed insight into the epigenetic reprogramming and transcriptional regulators involved in normal mammary gland developm...

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Detalles Bibliográficos
Autores principales: Chung, Chi-Yeh, Ma, Zhibo, Dravis, Christopher, Preissl, Sebastian, Poirion, Olivier, Luna, Gidsela, Hou, Xiaomeng, Giraddi, Rajshekhar R., Ren, Bing, Wahl, Geoffrey M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887110/
https://www.ncbi.nlm.nih.gov/pubmed/31597106
http://dx.doi.org/10.1016/j.celrep.2019.08.089