Sphingosine-1-phosphate Signalling drives an Angiogenic Transcriptional Programme in Diffuse Large B Cell Lymphoma

Although the over-expression of angiogenic factors is reported in diffuse large B-cell lymphoma (DLBCL), the poor response to anti-VEGF drugs observed in clinical trials suggests that angiogenesis in these tumours might be driven by VEGF-independent pathways. We show that sphingosine kinase-1 (SPHK1...

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Detalles Bibliográficos
Autores principales: Lupino, Lauren, Perry, Tracey, Margielewska, Sandra, Hollows, Robert, Ibrahim, Maha, Care, Matthew, Allegood, Jeremy, Tooze, Reuben, Sabbadini, Roger, Reynolds, Gary, Bicknell, Roy, Rudzki, Zbigniew, Hock, Ye Lin, Zanetto, Ulises, Wei, Wenbin, Simmons, William, Spiegel, Sarah, Woodman, Ciaran BJ, Rowe, Martin, Vrzalikova, Katerina, Murray, Paul G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887546/
https://www.ncbi.nlm.nih.gov/pubmed/31097785
http://dx.doi.org/10.1038/s41375-019-0478-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887546/
https://www.ncbi.nlm.nih.gov/pubmed/31097785
http://dx.doi.org/10.1038/s41375-019-0478-9

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