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NOTCH1 signaling in oral squamous cell carcinoma via a TEL2/SERPINE1 axis

Inactivating mutations in the EGF-like ligand binding domain of NOTCH1 are a prominent feature of the mutational landscape of oral squamous cell carcinoma (OSCC). In this study, we investigated NOTCH1 mutations in keratinocyte lines derived from OSCC biopsies that had been subjected to whole exome s...

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Detalles Bibliográficos
Autores principales: Salameti, Vasiliki, Bhosale, Priyanka G., Ames-Draycott, Ashley, Sipilä, Kalle, Watt, Fiona M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887571/
https://www.ncbi.nlm.nih.gov/pubmed/31827722
http://dx.doi.org/10.18632/oncotarget.27306