MiR‐195 and miR‐497 suppress tumorigenesis in lung cancer by inhibiting SMURF2‐induced TGF‐β receptor I ubiquitination

SMURF2 is a member of the HECT family of E3 ubiquitin ligases that have important roles as a negative regulator of transforming growth factor‐β (TGF‐β) signaling through ubiquitin‐mediated degradation of TGF‐β receptor I. However, the regulatory mechanism of SMURF2 is largely unknown. In this study,...

Descripción completa

Detalles Bibliográficos
Autores principales: Chae, Dong‐Kyu, Park, Jinyoung, Cho, Moonsoo, Ban, Eunmi, Jang, Mihue, Yoo, Young Sook, Kim, Eunice EunKyeong, Baik, Ja‐Hyun, Song, Eun Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887584/
https://www.ncbi.nlm.nih.gov/pubmed/31581360
http://dx.doi.org/10.1002/1878-0261.12581

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887584/
https://www.ncbi.nlm.nih.gov/pubmed/31581360
http://dx.doi.org/10.1002/1878-0261.12581

Ejemplares similares