FHR4‐based immunoconjugates direct complement‐dependent cytotoxicity and phagocytosis towards HER2‐positive cancer cells

Directing selective complement activation towards tumour cells is an attractive strategy to promote their elimination. In the present work, we have generated heteromultimeric immunoconjugates that selectively activate the complement alternative pathway (AP) on tumour cells. We used the C4b‐binding p...

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Detalles Bibliográficos
Autores principales: Seguin‐Devaux, Carole, Plesseria, Jean‐Marc, Verschueren, Charlène, Masquelier, Cécile, Iserentant, Gilles, Fullana, Marie, Józsi, Mihály, Cohen, Jacques H. M., Dervillez, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887587/
https://www.ncbi.nlm.nih.gov/pubmed/31365168
http://dx.doi.org/10.1002/1878-0261.12554

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887587/
https://www.ncbi.nlm.nih.gov/pubmed/31365168
http://dx.doi.org/10.1002/1878-0261.12554

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