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PIK3CA hotspot mutations in circulating tumor cells and paired circulating tumor DNA in breast cancer: a direct comparison study

Liquid biopsy analysis, mainly based on circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA), provides an extremely powerful tool for the molecular profiling of cancer patients in real time. In this study, we directly compared PIK3CA hotspot mutations (E545K, H1047R) in EpCAM‐positive CT...

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Detalles Bibliográficos
Autores principales: Tzanikou, Eleni, Markou, Athina, Politaki, Eleni, Koutsopoulos, Anastasios, Psyrri, Amanda, Mavroudis, Dimitris, Georgoulias, Vassilis, Lianidou, Evi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887588/
https://www.ncbi.nlm.nih.gov/pubmed/31254443
http://dx.doi.org/10.1002/1878-0261.12540