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miR‐367 as a therapeutic target in stem‐like cells from embryonal central nervous system tumors

Aberrant expression of the pluripotency factor OCT4A in embryonal tumors of the central nervous system (CNS) is a key factor that contributes to tumor aggressiveness and correlates with poor patient survival. OCT4A overexpression has been shown to up‐regulate miR‐367, a microRNA (miRNA) that regulat...

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Detalles Bibliográficos
Autores principales: Kaid, Carolini, Jordan, Dione, Bueno, Heloisa Maria de Siqueira, Araujo, Bruno Henrique Silva, Assoni, Amanda, Okamoto, Oswaldo Keith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887591/
https://www.ncbi.nlm.nih.gov/pubmed/31402560
http://dx.doi.org/10.1002/1878-0261.12562