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Three‐dimensional electron microscopy techniques for unravelling mitochondrial dysfunction in heart failure and identification of new pharmacological targets

A hallmark of heart failure is mitochondrial dysfunction leading to a bioenergetics imbalance in the myocardium. Consequently, there is much interest in targeting mitochondrial abnormalities to attenuate the pathogenesis of heart failure. This review discusses (i) how electron microscopy (EM) techni...

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Detalles Bibliográficos
Autores principales: Daghistani, Hussam M, Rajab, Bodour S, Kitmitto, Ashraf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887664/
https://www.ncbi.nlm.nih.gov/pubmed/30225980
http://dx.doi.org/10.1111/bph.14499