Designing Clinical Trials in Pediatric Nonalcoholic Steatohepatitis: Tips for Patient Selection and Appropriate Endpoints

Nonalcoholic fatty liver disease (NAFLD) is common in children and may progress to nonalcoholic steatohepatitis (NASH), advanced fibrosis, and even cirrhosis in childhood or early adulthood, indicating the need for pharmacologic treatment in this age group. Multiple trials are evaluating different t...

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Detalles Bibliográficos
Autores principales: Alkhouri, Naim, Kohli, Rohit, Feldstein, Ariel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887671/
https://www.ncbi.nlm.nih.gov/pubmed/31832567
http://dx.doi.org/10.1002/hep4.1449

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887671/
https://www.ncbi.nlm.nih.gov/pubmed/31832567
http://dx.doi.org/10.1002/hep4.1449

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