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A Pilot Genome‐Wide Analysis Study Identifies Loci Associated With Response to Obeticholic Acid in Patients With NASH

A significantly higher proportion of patients with nonalcoholic steatohepatitis (NASH) who received obeticholic acid (OCA) had histological improvement relative to placebo in the FLINT (farnesoid X nuclear receptor ligand obeticholic acid for noncirrhotic, NASH treatment) trial. However, genetic pre...

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Detalles Bibliográficos
Autores principales: Gawrieh, Samer, Guo, Xiuqing, Tan, Jingyi, Lauzon, Marie, Taylor, Kent D., Loomba, Rohit, Cummings, Oscar W., Pillai, Sreekumar, Bhatnagar, Pallav, Kowdley, Kris V., Yates, Katherine, Wilson, Laura A., Chen, Yii‐Der Ida, Rotter, Jerome I., Chalasani, Naga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887685/
https://www.ncbi.nlm.nih.gov/pubmed/31832568
http://dx.doi.org/10.1002/hep4.1439