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High Dietary Iron Disrupts Iron Homeostasis and Induces Amyloid-β and Phospho-τ Expression in the Hippocampus of Adult Wild-Type and APP/PS1 Transgenic Mice

BACKGROUND: Brain iron deposition is a feature of Alzheimer disease and may contribute to its development. However, the relative contribution of dietary iron remains unclear. OBJECTIVES: We investigated the impact of high dietary iron on brain pathological changes and cognitive function in adult wil...

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Detalles Bibliográficos
Autores principales: Chen, Min, Zheng, Jiashuo, Liu, Guohao, Zeng, Chong, Xu, En, Zhu, Wenjie, Anderson, Gregory J, Chen, Huijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887700/
https://www.ncbi.nlm.nih.gov/pubmed/31373375
http://dx.doi.org/10.1093/jn/nxz168