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High Dietary Iron Disrupts Iron Homeostasis and Induces Amyloid-β and Phospho-τ Expression in the Hippocampus of Adult Wild-Type and APP/PS1 Transgenic Mice
BACKGROUND: Brain iron deposition is a feature of Alzheimer disease and may contribute to its development. However, the relative contribution of dietary iron remains unclear. OBJECTIVES: We investigated the impact of high dietary iron on brain pathological changes and cognitive function in adult wil...
Autores principales: | Chen, Min, Zheng, Jiashuo, Liu, Guohao, Zeng, Chong, Xu, En, Zhu, Wenjie, Anderson, Gregory J, Chen, Huijun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887700/ https://www.ncbi.nlm.nih.gov/pubmed/31373375 http://dx.doi.org/10.1093/jn/nxz168 |
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