The Dichotomous Nature of AZ5104 (an EGFR Inhibitor) Towards RORγ and RORγT

The RORC (RAR related orphan receptor C) gene produces two isoforms by alternative promoter usage: RORγ (nuclear receptor ROR-gamma isoform 1) and RORγT (nuclear receptor ROR-gamma isoform 1). Both proteins have distinct tissue distributions and are involved in several physiological processes, inclu...

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Detalles Bibliográficos
Autores principales: Karaś, Kaja, Sałkowska, Anna, Karwaciak, Iwona, Walczak-Drzewiecka, Aurelia, Dastych, Jarosław, Bachorz, Rafał A., Ratajewski, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887705/
https://www.ncbi.nlm.nih.gov/pubmed/31744223
http://dx.doi.org/10.3390/ijms20225780

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887705/
https://www.ncbi.nlm.nih.gov/pubmed/31744223
http://dx.doi.org/10.3390/ijms20225780

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