Prostaglandin E2 Induces Skin Aging via E-Prostanoid 1 in Normal Human Dermal Fibroblasts

Collagen type I production decreases with aging, leading to wrinkles and impaired skin function. Prostaglandin E2 (PGE2), a lipid-derived signaling molecule produced from arachidonic acid by cyclo-oxygenase, inhibits collagen production, and induces matrix metallopeptidase 1 (MMP1) expression by fib...

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Detalles Bibliográficos
Autor principal: Shim, Joong Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887779/
https://www.ncbi.nlm.nih.gov/pubmed/31703303
http://dx.doi.org/10.3390/ijms20225555

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887779/
https://www.ncbi.nlm.nih.gov/pubmed/31703303
http://dx.doi.org/10.3390/ijms20225555

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