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The Proton Pump Inhibitor Omeprazole Does Not Promote Clostridioides difficile Colonization in a Murine Model

Proton pump inhibitor (PPI) use has been associated with microbiota alterations and susceptibility to Clostridioides difficile infections (CDIs) in humans. We assessed how PPI treatment alters the fecal microbiota and whether treatment promotes CDIs in a mouse model. Mice receiving a PPI treatment w...

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Detalles Bibliográficos
Autores principales: Tomkovich, Sarah, Lesniak, Nicholas A., Li, Yuan, Bishop, Lucas, Fitzgerald, Madison J., Schloss, Patrick D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887860/
https://www.ncbi.nlm.nih.gov/pubmed/31748246
http://dx.doi.org/10.1128/mSphere.00693-19