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Ammonium Gemini Surfactants Form Complexes with Model Oligomers of siRNA and dsDNA

Dimeric cationic surfactants (gemini-type) are a group of amphiphilic compounds with potential use in gene therapy as effective carriers for nucleic acid transfection (i.e., siRNA, DNA, and plasmid DNA). Our studies have shown the formation of lipoplexes composed of alkanediyl-α,ω-bis[(oxymethyl)dim...

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Detalles Bibliográficos
Autores principales: Andrzejewska, Weronika, Wilkowska, Michalina, Skrzypczak, Andrzej, Kozak, Maciej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887939/
https://www.ncbi.nlm.nih.gov/pubmed/31703275
http://dx.doi.org/10.3390/ijms20225546