Knockdown of Pyruvate Kinase M2 Inhibits Cell Proliferation, Metabolism, and Migration in Renal Cell Carcinoma

Emerging evidence indicates that the activity of pyruvate kinase M2 (PKM2) isoform is crucial for the survival of tumor cells. However, the molecular mechanism underlying the function of PKM2 in renal cancer is undetermined. Here, we reveal the overexpression of PKM2 in the proximal tubule of renal...

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Detalles Bibliográficos
Autores principales: Dey, Prasanta, Son, Ji Yeon, Kundu, Amit, Kim, Kyeong Seok, Lee, Yura, Yoon, Kyungsil, Yoon, Sungpil, Lee, Byung Mu, Nam, Ki Taek, Kim, Hyung Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887957/
https://www.ncbi.nlm.nih.gov/pubmed/31717694
http://dx.doi.org/10.3390/ijms20225622

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887957/
https://www.ncbi.nlm.nih.gov/pubmed/31717694
http://dx.doi.org/10.3390/ijms20225622

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