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Using PAR4 Inhibition as an Anti-Thrombotic Approach: Why, How, and When?
Protease-activated receptors (PARs) are a family of four GPCRs with a variety of cellular functions, yet the only advanced clinical endeavours to target these receptors for therapeutic gain to date relates to the impairment of platelet function for anti-thrombotic therapy. The only approved PAR anta...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888008/ https://www.ncbi.nlm.nih.gov/pubmed/31717963 http://dx.doi.org/10.3390/ijms20225629 |