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Using PAR4 Inhibition as an Anti-Thrombotic Approach: Why, How, and When?

Protease-activated receptors (PARs) are a family of four GPCRs with a variety of cellular functions, yet the only advanced clinical endeavours to target these receptors for therapeutic gain to date relates to the impairment of platelet function for anti-thrombotic therapy. The only approved PAR anta...

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Detalles Bibliográficos
Autores principales: Li, Simeng, Tarlac, Volga, Hamilton, Justin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888008/
https://www.ncbi.nlm.nih.gov/pubmed/31717963
http://dx.doi.org/10.3390/ijms20225629