RBM20 Regulates CaV1.2 Surface Expression by Promoting Exon 9* Inclusion of CACNA1C in Neonatal Rat Cardiomyocytes

The CACNA1C gene encodes for the CaV1.2 protein, which is the pore subunit of cardiac l-type voltage-gated calcium (Ca(2+)) channels (l-channels). Through alternative splicing, CACNA1C encodes for various CaV1.2 isoforms with different electrophysiological properties. Splice variants of CaV1.2 are d...

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Detalles Bibliográficos
Autores principales: Morinaga, Akihito, Ito, Jumpei, Niimi, Tomoaki, Maturana, Andrés D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888234/
https://www.ncbi.nlm.nih.gov/pubmed/31717392
http://dx.doi.org/10.3390/ijms20225591

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888234/
https://www.ncbi.nlm.nih.gov/pubmed/31717392
http://dx.doi.org/10.3390/ijms20225591

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