ANGPTL4 Induces TMZ Resistance of Glioblastoma by Promoting Cancer Stemness Enrichment via the EGFR/AKT/4E-BP1 Cascade

Glioblastoma (GBM) is the most aggressive type of brain tumor, with strong invasiveness and a high tolerance to chemotherapy. Despite the current standard treatment combining temozolomide (TMZ) and radiotherapy, glioblastoma can be incurable due to drug resistance. The existence of glioma stem-like...

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Detalles Bibliográficos
Autores principales: Tsai, Yu-Ting, Wu, An-Chih, Yang, Wen-Bin, Kao, Tzu-Jen, Chuang, Jian-Ying, Chang, Wen-Chang, Hsu, Tsung-I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888274/
https://www.ncbi.nlm.nih.gov/pubmed/31717924
http://dx.doi.org/10.3390/ijms20225625

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888274/
https://www.ncbi.nlm.nih.gov/pubmed/31717924
http://dx.doi.org/10.3390/ijms20225625

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