The Hypervariable Region of K-Ras4B Governs Molecular Recognition and Function

The flexible C-terminal hypervariable region distinguishes K-Ras4B, an important proto-oncogenic GTPase, from other Ras GTPases. This unique lysine-rich portion of the protein harbors sites for post-translational modification, including cysteine prenylation, carboxymethylation, phosphorylation, and...

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Detalles Bibliográficos
Autores principales: Abdelkarim, Hazem, Banerjee, Avik, Grudzien, Patrick, Leschinsky, Nicholas, Abushaer, Mahmoud, Gaponenko, Vadim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888304/
https://www.ncbi.nlm.nih.gov/pubmed/31739603
http://dx.doi.org/10.3390/ijms20225718

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888304/
https://www.ncbi.nlm.nih.gov/pubmed/31739603
http://dx.doi.org/10.3390/ijms20225718

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