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Tilivalline- and Tilimycin-Independent Effects of Klebsiella oxytoca on Tight Junction-Mediated Intestinal Barrier Impairment

Klebsiella oxytoca causes antibiotic-associated hemorrhagic colitis and diarrhea. This was attributed largely to its secreted cytotoxins tilivalline and tilimycin, inductors of epithelial apoptosis. To study whether Klebsiella oxytoca exerts further barrier effects, T84 monolayers were challenged wi...

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Detalles Bibliográficos
Autores principales: Hering, Nina A., Fromm, Anja, Bücker, Roland, Gorkiewicz, Gregor, Zechner, Ellen, Högenauer, Christoph, Fromm, Michael, Schulzke, Jörg-Dieter, Troeger, Hanno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888351/
https://www.ncbi.nlm.nih.gov/pubmed/31717457
http://dx.doi.org/10.3390/ijms20225595