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Tilivalline- and Tilimycin-Independent Effects of Klebsiella oxytoca on Tight Junction-Mediated Intestinal Barrier Impairment
Klebsiella oxytoca causes antibiotic-associated hemorrhagic colitis and diarrhea. This was attributed largely to its secreted cytotoxins tilivalline and tilimycin, inductors of epithelial apoptosis. To study whether Klebsiella oxytoca exerts further barrier effects, T84 monolayers were challenged wi...
Autores principales: | Hering, Nina A., Fromm, Anja, Bücker, Roland, Gorkiewicz, Gregor, Zechner, Ellen, Högenauer, Christoph, Fromm, Michael, Schulzke, Jörg-Dieter, Troeger, Hanno |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888351/ https://www.ncbi.nlm.nih.gov/pubmed/31717457 http://dx.doi.org/10.3390/ijms20225595 |
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