The Bile Acid-Phospholipid Conjugate Ursodeoxycholyl-Lysophosphatidylethanolamide (UDCA-LPE) Disintegrates the Lipid Backbone of Raft Plasma Membrane Domains by the Removal of the Membrane Phospholipase A2

The bile acid-phospholipid conjugate ursodeoxycholyl-lysophosphatidylethanolamide (UDCA-LPE) was shown to have anti-inflammatory, antisteatotic, and antifibrotic properties, rendering it as a drug targeting non-alcoholic steatohepatitis (NASH). On a molecular level, it disrupted the heterotetrameric...

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Detalles Bibliográficos
Autores principales: Stremmel, Wolfgang, Staffer, Simone, Fricker, Gert, Weiskirchen, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888454/
https://www.ncbi.nlm.nih.gov/pubmed/31717968
http://dx.doi.org/10.3390/ijms20225631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888454/
https://www.ncbi.nlm.nih.gov/pubmed/31717968
http://dx.doi.org/10.3390/ijms20225631

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