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Carboxypeptidase E-∆N Promotes Proliferation and Invasion of Pancreatic Cancer Cells via Upregulation of CXCR2 Gene Expression

Pancreatic cancer is one of the leading causes of cancer-related mortality worldwide. The molecular basis for the pathogenesis of this disease remains elusive. In this study, we have investigated the role of wild-type Carboxypeptidase E (CPE-WT) and a 40 kDa N-terminal truncated isoform, CPE-ΔN in p...

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Detalles Bibliográficos
Autores principales: Hareendran, Sangeetha, Yang, Xuyu, Lou, Hong, Xiao, Lan, Loh, Y. Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888591/
https://www.ncbi.nlm.nih.gov/pubmed/31731578
http://dx.doi.org/10.3390/ijms20225725