A Miniaturized Pump Out Method for Characterizing Molecule Interaction with ABC Transporters

Characterizing interaction of newly synthetized molecules with efflux pumps remains essential to improve their efficacy and safety. Caco-2 cell line cultivated on inserts is widely used for measuring apparent permeability of drugs across biological barriers, and for estimating their interaction with...

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Detalles Bibliográficos
Autores principales: Sevin, Emmanuel, Dehouck, Lucie, Versele, Romain, Culot, Maxime, Gosselet, Fabien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888615/
https://www.ncbi.nlm.nih.gov/pubmed/31698745
http://dx.doi.org/10.3390/ijms20225529

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888615/
https://www.ncbi.nlm.nih.gov/pubmed/31698745
http://dx.doi.org/10.3390/ijms20225529

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