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A Miniaturized Pump Out Method for Characterizing Molecule Interaction with ABC Transporters
Characterizing interaction of newly synthetized molecules with efflux pumps remains essential to improve their efficacy and safety. Caco-2 cell line cultivated on inserts is widely used for measuring apparent permeability of drugs across biological barriers, and for estimating their interaction with...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888615/ https://www.ncbi.nlm.nih.gov/pubmed/31698745 http://dx.doi.org/10.3390/ijms20225529 |