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Enhanced Therapeutic Potential of the Secretome Released from Adipose-Derived Stem Cells by PGC-1α-Driven Upregulation of Mitochondrial Proliferation

Peroxisome proliferator activated receptor λ coactivator 1α (PGC-1α) is a potent regulator of mitochondrial biogenesis and energy metabolism. In this study, we investigated the therapeutic potential of the secretome released from the adipose-derived stem cells (ASCs) transfected with PGC-1α (PGC-sec...

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Detalles Bibliográficos
Autores principales: Lee, Jaeim, Kim, Ok-Hee, Lee, Sang Chul, Kim, Kee-Hwan, Shin, Jin Sun, Hong, Ha-Eun, Choi, Ho Joong, Kim, Say-June
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888642/
https://www.ncbi.nlm.nih.gov/pubmed/31717375
http://dx.doi.org/10.3390/ijms20225589