Pyruvate Dehydrogenase and Tricarboxylic Acid Cycle Enzymes Are Sensitive Targets of Traumatic Brain Injury Induced Metabolic Derangement

Using a closed-head impact acceleration model of mild or severe traumatic brain injury (mTBI or sTBI, respectively) in rats, we evaluated the effects of graded head impacts on the gene and protein expressions of pyruvate dehydrogenase (PDH), as well as major enzymes of mitochondrial tricarboxylic ac...

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Detalles Bibliográficos
Autores principales: Lazzarino, Giacomo, Amorini, Angela Maria, Signoretti, Stefano, Musumeci, Giuseppe, Lazzarino, Giuseppe, Caruso, Giuseppe, Pastore, Francesco Saverio, Di Pietro, Valentina, Tavazzi, Barbara, Belli, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888669/
https://www.ncbi.nlm.nih.gov/pubmed/31744143
http://dx.doi.org/10.3390/ijms20225774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888669/
https://www.ncbi.nlm.nih.gov/pubmed/31744143
http://dx.doi.org/10.3390/ijms20225774

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