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Computational Nanoscopy of Tight Junctions at the Blood–Brain Barrier Interface

The selectivity of the blood–brain barrier (BBB) is primarily maintained by tight junctions (TJs), which act as gatekeepers of the paracellular space by blocking blood-borne toxins, drugs, and pathogens from entering the brain. The BBB presents a significant challenge in designing neurotherapeutics,...

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Detalles Bibliográficos
Autores principales: Rajagopal, Nandhini, Irudayanathan, Flaviyan Jerome, Nangia, Shikha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888702/
https://www.ncbi.nlm.nih.gov/pubmed/31717316
http://dx.doi.org/10.3390/ijms20225583