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Computational Nanoscopy of Tight Junctions at the Blood–Brain Barrier Interface
The selectivity of the blood–brain barrier (BBB) is primarily maintained by tight junctions (TJs), which act as gatekeepers of the paracellular space by blocking blood-borne toxins, drugs, and pathogens from entering the brain. The BBB presents a significant challenge in designing neurotherapeutics,...
Autores principales: | Rajagopal, Nandhini, Irudayanathan, Flaviyan Jerome, Nangia, Shikha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888702/ https://www.ncbi.nlm.nih.gov/pubmed/31717316 http://dx.doi.org/10.3390/ijms20225583 |
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