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Topological properties and in vitro identification of essential nodes of the Paclitaxel and Vincristine interactomes in PC-3 cells

BACKGROUND: Microtubule-targeting agents (MTAs) disrupt microtubule dynamics, thereby inducing apoptosis via mitochondrial pathway activation through the modulation in the expression of the Bcl-2 family. METHODS: To describe topological features of the MTAs networks associated to intrinsic apoptosis...

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Detalles Bibliográficos
Autores principales: Delgado-Carreño, Claudia, Méndez-Callejas, Gina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chang Gung University 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888721/
https://www.ncbi.nlm.nih.gov/pubmed/31783991
http://dx.doi.org/10.1016/j.bj.2019.04.003