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Topological properties and in vitro identification of essential nodes of the Paclitaxel and Vincristine interactomes in PC-3 cells
BACKGROUND: Microtubule-targeting agents (MTAs) disrupt microtubule dynamics, thereby inducing apoptosis via mitochondrial pathway activation through the modulation in the expression of the Bcl-2 family. METHODS: To describe topological features of the MTAs networks associated to intrinsic apoptosis...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Chang Gung University
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888721/ https://www.ncbi.nlm.nih.gov/pubmed/31783991 http://dx.doi.org/10.1016/j.bj.2019.04.003 |