HEATR1 deficiency promotes pancreatic cancer proliferation and gemcitabine resistance by up-regulating Nrf2 signaling

The human HEAT repeat-containing protein 1 (HEATR1), consisting of 2144 amino acids, is a member of the UTP10 family and contains one HEAT repeat at its C-terminal. HEATR1 has been reported to regulate cytotoxic T lymphocytes and rRNA synthesis, while its functions in tumors are poorly understood. H...

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Detalles Bibliográficos
Autores principales: Zhou, Yunjiang, Wang, Keke, Zhou, Yang, Li, Tao, Yang, Mengdi, Wang, Rui, Chen, Yaxin, Cao, Mengran, Hu, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888747/
https://www.ncbi.nlm.nih.gov/pubmed/31785531
http://dx.doi.org/10.1016/j.redox.2019.101390

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888747/
https://www.ncbi.nlm.nih.gov/pubmed/31785531
http://dx.doi.org/10.1016/j.redox.2019.101390

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