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Unique structural features in an Nramp metal transporter impart substrate-specific proton cotransport and a kinetic bias to favor import

Natural resistance-associated macrophage protein (Nramp) transporters enable uptake of essential transition metal micronutrients in numerous biological contexts. These proteins are believed to function as secondary transporters that harness the electrochemical energy of proton gradients by “coupling...

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Detalles Bibliográficos
Autores principales: Bozzi, Aaron T., Bane, Lukas B., Zimanyi, Christina M., Gaudet, Rachelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888756/
https://www.ncbi.nlm.nih.gov/pubmed/31619456
http://dx.doi.org/10.1085/jgp.201912428