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Unique structural features in an Nramp metal transporter impart substrate-specific proton cotransport and a kinetic bias to favor import
Natural resistance-associated macrophage protein (Nramp) transporters enable uptake of essential transition metal micronutrients in numerous biological contexts. These proteins are believed to function as secondary transporters that harness the electrochemical energy of proton gradients by “coupling...
Autores principales: | Bozzi, Aaron T., Bane, Lukas B., Zimanyi, Christina M., Gaudet, Rachelle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888756/ https://www.ncbi.nlm.nih.gov/pubmed/31619456 http://dx.doi.org/10.1085/jgp.201912428 |
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