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YY1 targets tubulin polymerisation-promoting protein to inhibit migration, invasion and angiogenesis in pancreatic cancer via p38/MAPK and PI3K/AKT pathways

BACKGROUND: Pancreatic cancer (PDAC) is a highly invasive cancer with poor prognosis. Recent research has found that the transcription factor Yin Yang 1 (YY1) plays an inhibitory role in the development of pancreatic cancer. It has been reported that tubulin polymerisation-promoting protein (TPPP) p...

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Detalles Bibliográficos
Autores principales: Chen, Qun, Yang, Chuang, Chen, Lei, Zhang, Jing-Jing, Ge, Wan-Li, Yuan, Hao, Meng, Ling-Dong, Huang, Xu-Min, Shen, Peng, Miao, Yi, Jiang, Kui-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888832/
https://www.ncbi.nlm.nih.gov/pubmed/31631174
http://dx.doi.org/10.1038/s41416-019-0604-5