TAMM41 is required for heart valve differentiation via regulation of PINK-PARK2 dependent mitophagy

TAMM41, located within the congenital heart diseases (CHD) sensitive region of 3p25 deletion syndrome, is a mitochondrial membrane maintenance protein critical for yeast survival, but its function in higher vertebrates remains unknown. Via in vivo zebrafish model, we found that tamm41 is highly expr...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Rui Meng, Tao, Jiong, Zhan, Ming, Yuan, Hao, Wang, Hai Hong, Chen, Sai Juan, Chen, Zhu, de Thé, Hugues, Zhou, Jun, Guo, Ying, Zhu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888875/
https://www.ncbi.nlm.nih.gov/pubmed/30824836
http://dx.doi.org/10.1038/s41418-019-0311-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888875/
https://www.ncbi.nlm.nih.gov/pubmed/30824836
http://dx.doi.org/10.1038/s41418-019-0311-z

Ejemplares similares