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TAMM41 is required for heart valve differentiation via regulation of PINK-PARK2 dependent mitophagy
TAMM41, located within the congenital heart diseases (CHD) sensitive region of 3p25 deletion syndrome, is a mitochondrial membrane maintenance protein critical for yeast survival, but its function in higher vertebrates remains unknown. Via in vivo zebrafish model, we found that tamm41 is highly expr...
Autores principales: | Yang, Rui Meng, Tao, Jiong, Zhan, Ming, Yuan, Hao, Wang, Hai Hong, Chen, Sai Juan, Chen, Zhu, de Thé, Hugues, Zhou, Jun, Guo, Ying, Zhu, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888875/ https://www.ncbi.nlm.nih.gov/pubmed/30824836 http://dx.doi.org/10.1038/s41418-019-0311-z |
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