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Platelet-activating factor (PAF) mediates NLRP3-NEK7 inflammasome induction independently of PAFR
The role of lipids in inflammasome activation remains underappreciated. The phospholipid, platelet-activating factor (PAF), exerts multiple physiological functions by binding to a G protein–coupled seven-transmembrane receptor (PAFR). PAF is associated with a number of inflammatory disorders, yet th...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888982/ https://www.ncbi.nlm.nih.gov/pubmed/31558613 http://dx.doi.org/10.1084/jem.20190111 |