ILC2s mediate systemic innate protection by priming mucus production at distal mucosal sites

Host immunity to parasitic nematodes requires the generation of a robust type 2 cytokine response, characterized by the production of interleukin 13 (IL-13), which drives expulsion. Here, we show that infection with helminths in the intestine also induces an ILC2-driven, IL-13–dependent goblet cell...

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Detalles Bibliográficos
Autores principales: Campbell, Laura, Hepworth, Matthew R., Whittingham-Dowd, Jayde, Thompson, Seona, Bancroft, Allison J., Hayes, Kelly S., Shaw, Tovah N., Dickey, Burton F., Flamar, Anne-Laure, Artis, David, Schwartz, David A., Evans, Christopher M., Roberts, Ian S., Thornton, David J., Grencis, Richard K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888984/
https://www.ncbi.nlm.nih.gov/pubmed/31582416
http://dx.doi.org/10.1084/jem.20180610

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888984/
https://www.ncbi.nlm.nih.gov/pubmed/31582416
http://dx.doi.org/10.1084/jem.20180610

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