Telomerase increasing compound protects hippocampal neurons from amyloid beta toxicity by enhancing the expression of neurotrophins and plasticity related genes

The telomerase reverse transcriptase protein, TERT, is expressed in the adult brain and its exogenic expression protects neurons from oxidative stress and from the cytotoxicity of amyloid beta (Aβ). We previously showed that telomerase increasing compounds (AGS) protected neurons from oxidative stre...

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Detalles Bibliográficos
Autores principales: Baruch-Eliyahu, Natalie, Rud, Vladislav, Braiman, Alex, Priel, Esther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889131/
https://www.ncbi.nlm.nih.gov/pubmed/31792359
http://dx.doi.org/10.1038/s41598-019-54741-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889131/
https://www.ncbi.nlm.nih.gov/pubmed/31792359
http://dx.doi.org/10.1038/s41598-019-54741-7

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