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MicroRNA-222 reprogrammed cancer-associated fibroblasts enhance growth and metastasis of breast cancer

BACKGROUND: Cancer-associated fibroblasts (CAFs) are known to impact on tumour behaviour, but the mechanisms controlling this are poorly understood. METHODS: Breast normal fibroblasts (NFs) or CAFs were isolated from cancers by laser microdissection or were cultured. Fibroblasts were transfected to...

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Detalles Bibliográficos
Autores principales: Chatterjee, Annesha, Jana, Samir, Chatterjee, Soumya, Wastall, Laura M, Mandal, Gunjan, Nargis, Nelofar, Roy, Himansu, Hughes, Thomas A, Bhattacharyya, Arindam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889135/
https://www.ncbi.nlm.nih.gov/pubmed/31481734
http://dx.doi.org/10.1038/s41416-019-0566-7