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CBP and SRF co-regulate dendritic growth and synaptic maturation

The CREB-binding protein (CBP) exerts tight control of developmental processes. Here, we investigated the consequences of its selective ablation in newborn neurons. Mice in which CBP was eliminated during neuronal differentiation showed perinatal death and defective diaphragm innervation. Adult-born...

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Detalles Bibliográficos
Autores principales: del Blanco, Beatriz, Guiretti, Deisy, Tomasoni, Romana, Lopez-Cascales, María T., Muñoz-Viana, Rafael, Lipinski, Michal, Scandaglia, Marilyn, Coca, Yaiza, Olivares, Román, Valor, Luis M., Herrera, Eloísa, Barco, Angel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889142/
https://www.ncbi.nlm.nih.gov/pubmed/30850733
http://dx.doi.org/10.1038/s41418-019-0285-x