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p53 nuclear accumulation as an early indicator of lethal prostate cancer

BACKGROUND: After radical prostatectomy (RP) for prostate cancer (PC), p53 alterations predict biochemical relapse (BCR), however, recent evidence suggests that metastatic relapse (MR) not BCR is a surrogate for PC specific mortality (PCSM). This updated analysis of a previously published study inve...

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Detalles Bibliográficos
Autores principales: Quinn, David I., Stricker, Phillip D., Kench, James G., Grogan, Judith, Haynes, Anne-Maree, Henshall, Susan M., Grygiel, John J., Delprado, Warick, Turner, Jennifer J., Horvath, Lisa G., Mahon, Kate L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889144/
https://www.ncbi.nlm.nih.gov/pubmed/31409910
http://dx.doi.org/10.1038/s41416-019-0549-8