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p53 nuclear accumulation as an early indicator of lethal prostate cancer
BACKGROUND: After radical prostatectomy (RP) for prostate cancer (PC), p53 alterations predict biochemical relapse (BCR), however, recent evidence suggests that metastatic relapse (MR) not BCR is a surrogate for PC specific mortality (PCSM). This updated analysis of a previously published study inve...
Autores principales: | Quinn, David I., Stricker, Phillip D., Kench, James G., Grogan, Judith, Haynes, Anne-Maree, Henshall, Susan M., Grygiel, John J., Delprado, Warick, Turner, Jennifer J., Horvath, Lisa G., Mahon, Kate L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889144/ https://www.ncbi.nlm.nih.gov/pubmed/31409910 http://dx.doi.org/10.1038/s41416-019-0549-8 |
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