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Chimeric antigen receptor macrophage therapy for breast tumours mediated by targeting the tumour extracellular matrix
BACKGROUND: The extracellular matrix (ECM) is essential for malignant tumour progression, as it is a physical barrier to various kinds of anticancer therapies. Matrix metalloproteinase (MMPs) can degrade almost all ECM components, and macrophages are an important source of MMPs. Studies using macrop...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889154/ https://www.ncbi.nlm.nih.gov/pubmed/31570753 http://dx.doi.org/10.1038/s41416-019-0578-3 |