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Chimeric antigen receptor macrophage therapy for breast tumours mediated by targeting the tumour extracellular matrix

BACKGROUND: The extracellular matrix (ECM) is essential for malignant tumour progression, as it is a physical barrier to various kinds of anticancer therapies. Matrix metalloproteinase (MMPs) can degrade almost all ECM components, and macrophages are an important source of MMPs. Studies using macrop...

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Detalles Bibliográficos
Autores principales: Zhang, Wenlong, Liu, Ling, Su, HuiFang, Liu, Qin, Shen, Jie, Dai, Hanren, Zheng, Wei, Lu, Yan, Zhang, Weijie, Bei, Yuncheng, Shen, Pingping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889154/
https://www.ncbi.nlm.nih.gov/pubmed/31570753
http://dx.doi.org/10.1038/s41416-019-0578-3