Cargando…

Chimeric antigen receptor macrophage therapy for breast tumours mediated by targeting the tumour extracellular matrix

BACKGROUND: The extracellular matrix (ECM) is essential for malignant tumour progression, as it is a physical barrier to various kinds of anticancer therapies. Matrix metalloproteinase (MMPs) can degrade almost all ECM components, and macrophages are an important source of MMPs. Studies using macrop...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Wenlong, Liu, Ling, Su, HuiFang, Liu, Qin, Shen, Jie, Dai, Hanren, Zheng, Wei, Lu, Yan, Zhang, Weijie, Bei, Yuncheng, Shen, Pingping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889154/ https://www.ncbi.nlm.nih.gov/pubmed/31570753 http://dx.doi.org/10.1038/s41416-019-0578-3

Ejemplares similares

Efficacy evaluation of chimeric antigen receptor-modified human peritoneal macrophages in the treatment of gastric cancer
por: Dong, Xuhui, et al.
Publicado: (2023)

Chimeric Antigen Receptors Modified T-Cells for Cancer Therapy
por: Dai, Hanren, et al.
Publicado: (2016)

Engineering chimeric antigen receptor T cells for solid tumour therapy
por: Liu, Longwei, et al.
Publicado: (2022)

M2 tumour-associated macrophages contribute to tumour progression via legumain remodelling the extracellular matrix in diffuse large B cell lymphoma
por: Shen, Long, et al.
Publicado: (2016)

Linked in: the extracellular matrix network in tumour dissemination
por: Leb‐Reichl, V., et al.
Publicado: (2020)

Intervening pyruvate carboxylase stunts tumor growth by strengthening anti-tumor actions of tumor-associated macrophages
por: Shu, Yuxin, et al.
Publicado: (2022)

Decorin is a pivotal effector in the extracellular matrix and tumour microenvironment
por: Zhang, Wen, et al.
Publicado: (2018)

Endothelial extracellular vesicles promote tumour growth by tumour‐associated macrophage reprogramming
por: Njock, Makon‐Sébastien, et al.
Publicado: (2022)

Concepts of extracellular matrix remodelling in tumour progression and metastasis
por: Winkler, Juliane, et al.
Publicado: (2020)

Cancer Extracellular Matrix Proteins Regulate Tumour Immunity
por: Gordon-Weeks, Alex, et al.
Publicado: (2020)

Immunohistochemical characterisation of extracellular matrix components of salivary gland tumours.
por: Nara, Y., et al.
Publicado: (1991)

Cancer-associated fibroblasts-derived HAPLN1 promotes tumour invasion through extracellular matrix remodeling in gastric cancer
por: Zhang, Tiancheng, et al.
Publicado: (2021)

Novel lectin-based chimeric antigen receptors target Gb3-positive tumour cells
por: Meléndez, Ana Valeria, et al.
Publicado: (2022)

Anti-Apoptotic c-FLIP Reduces the Anti-Tumour Activity of Chimeric Antigen Receptor T Cells
por: Tan, Grace Min Yi, et al.
Publicado: (2022)

Expression of the extracellular matrix protein tenascin in malignant and benign ovarian tumours.
por: Wilson, K. E., et al.
Publicado: (1996)

A Novel Method for Simulating the Extracellular Matrix in Models of Tumour Growth
por: Toma, Alina, et al.
Publicado: (2012)

The role of extracellular matrix in tumour angiogenesis: the throne has NOx servants
por: Alsharabasy, Amir M., et al.
Publicado: (2020)

Colonial morphology of tumour cells and susceptibility to cytolysis by tumour necrosis factor. The role of cellular fibronectin deposition in the extracellular matrix.
por: Neale, M. L., et al.
Publicado: (1990)

Phase I study of chimeric antigen receptor modified T cells in treating HER2-positive advanced biliary tract cancers and pancreatic cancers
por: Feng, Kaichao, et al.
Publicado: (2017)

PD-1 silencing impairs the anti-tumor function of chimeric antigen receptor modified T cells by inhibiting proliferation activity
por: Wei, Jianshu, et al.
Publicado: (2019)

Anaphylactic tests for tumour antigen in transplantable animal tumours.
por: Dale, M. M.
Publicado: (1966)

Tumour-associated macrophages: versatile players in the tumour microenvironment
por: Ji, Zoey Zeyuan, et al.
Publicado: (2023)

Extracellular matrix density regulates the formation of tumour spheroids through cell migration
por: Gonçalves, Inês G., et al.
Publicado: (2021)

Interrelationships between the extracellular matrix and the immune microenvironment that govern epithelial tumour progression
por: Kolesnikoff, Natasha, et al.
Publicado: (2022)

Enhanced Detection of Desmoplasia by Targeted Delivery of Iron Oxide Nanoparticles to the Tumour-Specific Extracellular Matrix
por: Chopra, Meenu, et al.
Publicado: (2021)

Distribution of Photofrin between tumour cells and tumour associated macrophages.
por: Korbelik, M., et al.
Publicado: (1991)

CDK5 Inhibition Abrogates TNBC Stem‐Cell Property and Enhances Anti‐PD‐1 Therapy
por: Bei, Yuncheng, et al.
Publicado: (2020)

Radioimmunoassay of Tumour Specific Transplantation Antigen of a Chemically Induced Rat Sarcoma: Circulating Soluble Tumour Antigen in Tumour Bearers
por: Thomson, D. M. P., et al.
Publicado: (1973)

The Walter Herbert Lecture. Control of cell motility and tumour invasion by extracellular matrix interactions.
por: Ruoslahti, E.
Publicado: (1992)

Bimodal magnetic resonance and optical imaging of extracellular matrix remodelling by orthotopic ovarian tumours
por: Bochner, Filip, et al.
Publicado: (2020)

Chimeric antigen receptor T cells targeting FcRH5 provide robust tumour-specific responses in murine xenograft models of multiple myeloma
por: Jiang, Dongpeng, et al.
Publicado: (2023)

Chimeric antigen-guiding extracellular vesicles eliminate antigen-specific Th2 cells in subjects with food allergy
por: Zhang, Yuan-Yi, et al.
Publicado: (2021)

Tumour antigenicity in ovarian cancer.
por: Levin, L., et al.
Publicado: (1975)

Urokinase and macrophages in tumour angiogenesis.
por: Hildenbrand, R., et al.
Publicado: (1995)

HLA-dependent tumour development: a role for tumour associate macrophages?
por: Marchesi, Maddalena, et al.
Publicado: (2013)

An apoptosis-driven ‘onco-regenerative niche’: roles of tumour-associated macrophages and extracellular vesicles
por: Gregory, Christopher D., et al.
Publicado: (2018)

Dominant-negative transforming growth factor-β receptor-armoured mesothelin-targeted chimeric antigen receptor T cells slow tumour growth in a mouse model of ovarian cancer
por: Li, Ke, et al.
Publicado: (2022)

Tumour Derived Extracellular Vesicles: Challenging Target to Blunt Tumour Immune Evasion
por: Lopatina, Tatiana, et al.
Publicado: (2022)

Tissue-Specific Human Extracellular Matrix Scaffolds Promote Pancreatic Tumour Progression and Chemotherapy Resistance
por: Al-Akkad, Walid, et al.
Publicado: (2022)

Role for extracellular vesicles in the tumour microenvironment
por: O'Loghlen, Ana
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_4ias8osrnjs15tjkokaiaqqm1i